Terry M. Phillips, PhD, DSc
Resource Chief
National Institutes of Health, Bethesda, MD, USA

"I am delighted with the NanoDrop 3300 fluorospectrometer. The instrument has already proven its worth in being able to give us an accurate analysis of dye-labeled antibodies in ultra micro samples. Many of our reagents are obtained directly from patients and are, therefore, of limited supply. As I am an analytical immunologist evaluating patient reactions to a variety of antigenic stimuli in a variety of different biological fluids, the ability to assess labeling efficiency in micro qualities of a protein solution is invaluable. The NanoDrop not only accurately accomplishes this task but with a little care enables us to reclaim the majority of the sample.  I feel the NanoDrop 3300 fluorospectrometer should be an integral part of any protein and/or clinical lab. Thank you again for making such a unique and valuable instrument."

Salvatore A.E. Marras, PhD
Senior Research Associate
Public Health Research Institute, Newark, NJ USA

"We are very pleased with the performance of the NanoDrop 3300 Fluorospectrometer. We use the instrument to monitor the hybridization of molecular beacon probes with artificial DNA oligonucleotide targets. Upon hybridization of a molecular beacon probe to a DNA target, the molecular beacon probe emits fluorescent light. The fluorospectrometer is very sensitive in measuring the fluorescence increase upon the hybridization of the molecular beacon probe to a DNA target. In addition, it requires only small amounts of both molecular beacon probe and DNA target. The advantage of the fluorospectrometer, besides its small sample volume, is its broad range of excitation wavelengths and its broad range in detecting emission wavelengths. This allows us to reliably characterize a wide range of molecular beacon probes, each labeled with a different colored fluorophore."

Serge J. Edmé, PhD
Research Geneticist
USDA-ARS, Sugarcane Field Station, Canal Point, FL USA

"The NanoDrop 3300 fluorospectrometer is simple to use but also has great capability and flexibility built in. User-controlled settings in the software are useful features. I like the NanoDrop 3300 for the versatility in the types of samples and measurements it will handle. The small sample size, small foot print, and lack of both cuvettes and filter changes are all key attributes of the instrument that are important to our lab."

Linda K. Dick, PhD
Post Doctoral Researcher
School of Environment and Natural Resources
The Ohio State University, Columbus, OH USA

"The NanoDrop 3300 Fluorospectrometer has been a great addition to our lab, especially given our space constraints. We have been using the PicoGreen assay, and the small sample volume required (2 uL) is a real advantage when DNA yield is low to begin with. It is easy to clean between samples when compared with rinsing cuvettes. It is rapid and easy to use, and readings are quite reproducible when done using the same standard curve. We have found that once we know the approximate range of DNA concentrations for our samples, we only need to run a couple of standards."

Danelle C. Smith
Research Associate
H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL USA

"Before I came to this laboratory, I worked at The Johns Hopkins University with tissue samples-which I quantitated with the NanoDrop 1000 spectrophotometer. I loved the NanoDrop 1000 so much: I requested that my current lab use this spectrophotometer for quanitation. In my current lab they had previously quantitated DNA using the standard PicoGreen fluorescence method-but the large sample volume needed for measurement with cuvette based fluorometers or a platereader jeopardized our ability to continue with our assays. Since our sample yields were so small and below detection for the NanoDrop 1000 we needed to measure using the PicoGreen assay. Fortunately, NanoDrop had presented their newest product-NanoDrop 3300. This wonderful instrument allows us to measure our small samples using PicoGreen assay, and is quite versatile for other assays. The small sample size, the instruments versatility, and the space saving size of the equipment, should be a requirement for every lab."