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How It Works


Pedestal Measurements

The patented sample retention system used by The Thermo Scientific
NanoDrop 2000 and NanoDrop™ 2000c allows for the analysis of
0.5 µl - 2.0 µl samples, without the need for cuvettes or capillaries.

With the arm open, a sample is pipetted directly onto the pedestal.





After the arm is closed, a sample column is formed.




The pedestal then moves to automatically adjust for an optimal
path length (0.05 mm - 1 mm).




When the measurement is complete, the surfaces are simply wiped
with a lint-free lab wipe before going on to the next sample.

Cuvette Measurements

The NanoDrop 2000c model includes a built-in cuvette capability.
Most common cuvettes and micro-cuvettes may be used with this
instrument (8.5 mm z-height and 2 mm beam).

Multi-Sample Measurements

The NanoDrop 8000 model allows up to eight micro-volume samples
(0.5 µl - 2.0 µl) to be measured simultaneously. With the arm open,
up to eight samples are pipetted directly onto the optical pedestals.




After the arm is closed, sample columns are formed and held in place
by surface tension during measurement.

Fluorescence Measurements

The NanoDrop 3300 model allows fluorescence analysis of micro-volume samples. With the arm open, a fluorescent sample is pipetted directly
onto the pedestal.




After the arm is closed, a sample column is formed and held in place
by surface tension during the fluorescence measurement.

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